By Worsnop and Flint
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Source: Pediatric Dermatology. db=pubmed&cmd=Retrieve&dopt=A bstractPlus&list_uids=11860570&query_hl=4&itool=pubmed_docsum • Variable limb malformations in the Brachmann-Cornelia de Lange syndrome. Author(s): Pashayan HM, Fraser FC, Pruzansky S. Source: Birth Defects Orig Artic Ser. db=pubmed&cmd=Retrieve&dopt=A bstractPlus&list_uids=1218207&query_hl=6&itool=pubmed_docsum • X-linked Cornelia de Lange syndrome owing to SMC1L1 mutations. Author(s): Musio A, Selicorni A, Focarelli ML, Gervasini C, Milani D, Russo S, Vezzoni P, Larizza L.
By noticing patterns of disorders among relatives, healthcare professionals can determine whether an individual, other family members, or future generations may be at an increased risk of developing a particular condition. A family medical history can identify people with a higher-than-usual chance of having common disorders, such as heart disease, high blood pressure, stroke, certain cancers, and diabetes. These complex disorders are influenced by a combination of genetic factors, environmental conditions, and lifestyle choices.
Nucleotides are arranged in two long strands that form a spiral called a double helix. The structure of the double helix is somewhat like a ladder, with the base pairs forming the ladder’s rungs and the sugar and phosphate molecules forming the vertical sidepieces of the ladder. An important property of DNA is that it can replicate, or make copies of itself. Each strand of DNA in the double helix can serve as a pattern for duplicating the sequence of bases. This is critical when cells divide because each new cell needs to have an exact copy of the DNA present in the old cell.
Advanced Practical Physics for Students by Worsnop and Flint